| S.C.I. - Special Criminal Investigation |
| Sadakichi Nanaban Series Hideyoshi no Ougon |
| Salamander |
| Samurai Ghost |
| Sekigahara |
| Sengoku Mahjong |
| Shanghai |
| Shinobi |
| Shiryou Sensen |
| ShockMan |
| Shougi Shodan Icchokusen |
| Shougi Shoshinsha Muyou |
| Side Arms - Hyper Dyne |
| Silent Debuggers |
| Sindibad - Chitei no Daimakyuu |
| Sinistron |
| Skweek |
| Soldier Blade |
| Soldier Blade Special - Caravan Stage |
| Somer Assault |
| Son Son II |
| Sonic Spike - World Championship Beach Volleyball |
| Space Harrier |
| Space Invaders - Fukkatsu no Hi |
| Spin Pair |
| Spiral Wave |
| Splatterhouse |
| Stratego |
| Street Fighter II' - Champion Edition |
| Strip Fighter II |
| Super Mario Bros |
| Super Metal Crusher |
| Super Momotarou Dentetsu |
| Super Momotarou Dentetsu II |
| Super Star Soldier |
| Super Volley Ball |
| Susanoou Densetsu |
